Double or Nothing? Cell Division and Cell Size Control
نویسندگان
چکیده
منابع مشابه
A Model for Cell Population Size Control Using Asymmetric Division
In multicellular organisms one can find examples where a growing tissue divides up until some final fixed cell number. Asymmetric division plays a prevalent feature in tissue differentiation in these organisms, where the daughters of each asymmetric division inherit unequal amounts of a fate determining molecule and as a result follow different developmental fates. In some tissues the accumulat...
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The determination of cell size in multicellular organisms is intimately linked to the relationship between growth and cell division. The term growth has been widely used in biology to describe processes including progression through a developmental programme, cell differentiation, cell division and increase in mass. Here, we use the term growth solely to indicate mass increase. Growing tissues ...
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Cells of a given type maintain a characteristic cell size to function efficiently in their ecological or organismal context. They achieve this through the regulation of growth rates or by actively sensing size and coupling this signal to cell division. We focus this review on potential size-sensing mechanisms, including geometric, external cue, and titration mechanisms. Mechanisms that titrate ...
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Cells usually grow to a proper size before they divide. To ensure an optimal size for cell survival and function, it is crucial that cells develop efficient and sensitive mechanisms for cell-size control. in 2009, 2 independent studies proposed that the DyRK-family kinase Pom1 could serve as a cell-length sensor to negatively regulate mitotic entry through sAD-like kinase Cdr2 in fission yeast....
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ژورنال
عنوان ژورنال: Trends in Plant Science
سال: 2019
ISSN: 1360-1385
DOI: 10.1016/j.tplants.2019.09.005